Description Hyaluronan isacolorless,transparent,viscoelastic,biodegradable,non-pyrogenic and sterile gel, supplied in aprefilledglasssyringe. Hyaluronan consistsofcross-linkedsodiumhyaluronatefrombiofermentationandformulated to a concentration of 20 mg/ml,suspended in a physiological buffer pH 7.Sodium hyaluronate is a natural polymer ofrepeatingdisaccharideunitsof N-acetyl-D-glucosamine andsodiumglucuronate linked by glycosidic bonds, whichis widely distributed in the extracellular matrixin both animals and human. After slightlycross-linking, italsohasgoodbiocompatibility. Hyaluronan is supplied in adisposable glass syringe with a luer-lockfitting. The syringe is equipped with a plungerstopper, finger grip and plunger rod andpacked in a blister together with two sterileneedles.
Specification Content: Sodium hyaluronate, cross-linked:20mg/ml Physiological sodium chloride phosphate buffer:q.s. PH: 6.8-7.5 Volume:1.0 ml One package of Hyaluronan contains a syringe and two sterile 27G needles. Dosage Defects should be fully corrected but not overcorrected, a maximum dosage of 1.5ml per injection site is recommended. Treatment procedure Hyaluronan should be used after indoor temperature balance. LocaI anaIgesia(ice,topical analgesics or local infiltration, and/or nerve block with 1% lidocaine solution) is provided beforetreatmenat the discretion of the doctor. Before injection,press the rod carefully until a small droplet is visible at the tipof the needle. Inject Hyaluronan while pullingtheneedleslowlybackwardsandstopinjecting just before the needle pulled outfrom the skin to prevent material from leakingout from the injection site. Oncetheinjetion is completed, the injectionsiteismanuallymassaged toallow Hyaluronan to conform to thecontours of the adjacent tissues. After injection, if the treated area is swollen,melting ice can be applied on the site for a short period. Warning Hyaluronan is for single use only. Do not use if package is opened or damaged. Do not restedlize Hyaluronan as this may damage or alter the product. Do not inject intravascularly. Do not use Hyaluronan with other fillers. Adverse effections Inflammatory reaction to Hyaluronan has been observed with swelling, redness, tenderness, induration and rarely acneform papules at the injection site after the initial treatment. Average duration of this effect is no more than 2 weeks. Storage Hyaluronan has to be storedbetween 2 ~ 250C in a dry place and shouldbe protected from sunlight, heat and frost. Shelf life 36 months under recommended conditions.